Comparison of hydroxyethylstarch 130/0.4 and ringer’s lactate on fibrinogen level in caesarean operations: a randomized clinical trial

COMPARISON OF HYDROXYETHYLSTARCH 130/0.4 AND RINGER’S LACTATE ON FIBRINOGEN LEVEL IN CAESAREAN OPERATIONS: A RANDOMIZED CLINICAL TRIAL
 Background and Aim:
 Colloids are effective in volume resuscitation but they have been shown to negative impacts on fibrin formation. The aim of this study is evaluate the effect using low dose HES solutions fibrinogen level caserean operations.
 Materials methods: 
 100 women, scheduled for Caserean surgery with spinal anesthesia were enrolled study. Patients assigned receive hydroxyethyl starch (HES) addition a basic infusion Ringer’s lactate (RL) solution (GROUP HES) or exclusively RL throughout intraoperative period RL). Group received 8 ml.kg-1h-1 5 mL.kg-1.h-1 20 mL kg-1.h-1. Fibrinogen, haemoglobin, platelet values recorded preoperatively at postoperative first hour.
 Results:
 was used only HES, amount consumed 418 ± 90 mL. consumption 276 58 1197 197 RL. There significant change haemoglobine before after between groups. mean decrease 92.18 ±60.12 mg/dL 65.70 83.61 RL.
 Conclusion:
 can be elective Caeserean operations without predicted active hemorrhage. When there hemorrhage any reason cases, must anticipated rapid replacement kept mind.